C.V.

• PhD 1976 in Immunology, National Institute for Medical Research, Mill Hill, London

• Postdoctoral training in Biology, California Institute of Technology (1976-77) and in Microbiology, University of California at Los Angeles (1977-79).

• Scientific staff, Parasitology, National Institute for Medical Research (1979-1983).

• Lecturer/Reader/Professor in Parasite Immunology, Biology Department, Imperial College (1983-1995).

• Professor of Zoology, University of Edinburgh since 1995.

Research groupings

Parasitology
Immunology

Teaching

Parasitology

Research interests

Parasites which live in mammalian hosts for long periods have evolved an array of mechanisms for diverting and manipulating the host immune response. We are studying the interaction between nematode parasites and the immune system in order to understand parasite survival, to devise new means of shifting the balance towards protective immunity, and to isolate novel molecules from nematode parasites which modify immune responses. Current projects include characterisation of secreted proteins which drive Th2 responses; analysis of genes expressed at the time of parasite invasion; definition of the major T cell antigens in infection; study of the surface coat of nematode parasites; and the search for cytokine-like proteins encoded within parasite genomes.